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Areca Nut Extract Arecoline/Arecoline Hydrobromide GMP Supplier

Product Introduction

Product Name: Super Quality Areca Catechu Powder, Areca Catechu Nut Extract with 98% Arecoline   

Latin Name: Areca catechu

CAS No.:300-08-3

Appearance:Light brown to white powder

MF:C₈H₁₃NO₂.HBr

Molecular Weight: 236.11

Extraction Type: Solvent Extraction

Test method: HPLC/UV

Grade: Food and pharma grade

Specification: 98%

Chromatogram

Test Report:

Product Name:	Arecoline Hydrobromide
Chemical Name:	Methyl-1,2,5,6-tetrahydro-1-methyl nicotinate
Molecular Formula:	C8H13NO2 .HBr
Batch No.	20160612
Analysis Date:	2016-06-12
Expiry Date:	2018-06-11
Structural Formula:
CAS No.:	300-08-3
Test	Limits	Results
Appearance	A white Crystalline Powder	A White Crystalline Powder
Melting point, (C)	171~173	171~172

Ident (GC-MS)	As standards	Conforms
Assay % (calculated on the dried substance)	98.0~ 100.0	99.2%
Loss on drying, %	Not more than .0.5	0.3
Heavy metal	10ppm Max.	Confirm
Solution(water)	Clear and Transparent .	Clear and Transparent
Storage conditions	Store the container tightly closed in a dry and cool place

Function:

(1)It has the heart stimulating effectarecoline hydrobromide.

(2)Anti-cancer and anti inflammatoryarecoline hydrobromide.
(3)It can be used to local anesthesia, refrigeration, anti-inflammation and detumescencearecoline hydrobromide.

(4)It used in sweating profusely with body temperature dropping; muscle spasm in choleraarecoline hydrobromide.

(5)It used in the treatment of rheumatism, intermittent fevers and acute inflammatory infectionsarecoline hydrobromide.

Application:

Owing to its muscarinic and nicotinic agonist properties, arecoline has shown improvement in the learning ability of healthy volunteers. Since one of the hallmarks of Alzheimer's disease is a cognitive decline, arecoline was suggested as a treatment to slow down this process and arecoline administered intravenously did indeed show modest verbal and spatial memory improvement in Alzheimer's patients, though due to arecoline's possible carcinogenic properties,it is not the first drug of choice for this degenerative disease.

Arecoline has also been used medicinally as an antihelmintic (a drug against parasitic worms).

Extract Powder Process:

GMP Certificate