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What is Salvia extract (Danshen extract)?

Danshen is one of the most popular healing herbs used today throughout the world. It increases mental and physical efficiency and resistance to stress and disease. Danshen's adaptogenic funtion help balance the body, depending on the individual's needs. It is known to normalize blood pressure, increase blood circulation and aid in the prevention of heart disease.

Physical Properties:

Features: A pure compound extracted from Salvia miltiorrhiza, is believed effectively against coronary heart disease through danshensu injection. Solubility: Solvable in water, ethanol and methyl alcohol.

Specification: 5%-60%, HPLC

Active ingredients: Salvianolic Acid B

Molecular Mass: 718.6138

Molecular Formula: C36H30O16

Main Functions of Salvia extract:

1. Enhancing immunity and the ability of antivirus and infection.

2. Anti-aging, anti-oxidant , antifatigue, adjusting cerebral nervous system, enhancing hematopoietic function and promoting metabolism.

3. Protecting hematopoietic function of marrow, improving the ability of hepatic detoxifcatio and promoting. Restoration of hepatic tissue.

4. Preventing and treating coronary heart disease, climacteric syndrome, diabetes, high blood pressure, anemia, etc.

5. Preventing cancer, activating normal cell and   improving the blood circulation.

Application Fields:

1. Applied in pharmaceutical field, Tanshinones is mainly used as raw material for clearing heat, anti-inflammation, detumescence and increasing coronary flow.
2. Applied in food additives, it owns the effect of antifatigue, anti-aging and nourishing brain.

3. Applied in cosmetics field, it owns the effect of whitening, anti-aging, anti-wrinkle,anti-oxidant, activating skin Cells, making skin more tender and firm.

Clinical Applications:  

1. To expend vessel.

2. Depress blood pressure.

3. Anti-thrombotic.

4 Antioxidant.

Package:

1. 25kg/drum (25kg net weight,28kg gross weight; Packed in a cardboard-drum with two plastic-bags inside. Drum Size: 510mm high, 350mm diameter) ; 

2. 1kg/bag (1kg net weight, 1.2kg gross weight, packed in an aluminum foil bag inside and paper carton outside ) or as per your request.

Storage:

Keep in cool, dry and protecting from direct strong light and heat.  

Advantage of product:

Clinical Application: 

1>. To expend vessel; 

2>. Depress blood pressure;

3>. Anti-thrombotic; 4>Antioxidant

Red sage or Danshen ( Salvia miltiorrhiza ) Root An antioxidant called salvianolic acid (or salvianolic acid B) isolated from Danshen is under study for protection against cerebrovascular disorders.[9][13]Tanshinone IIA is one of the most abundant constituents of the root of Salvia miltiorrhiza which exerts antioxidant and anti-inflammatory actions in many experimental disease models,[16][17]

Results from animal and human studies support the use of 

Danshen for circulatory disorders to some extent because it is known to decrease the 

blood's ability to clot in at least two ways. 

First, it limits the stickiness of blood platelets. 

It also decreases the production of fibrin, the threads of protein that trap blood cells to form clots. 

Both these effects help to improve blood circulation. In addition, chemicals in danshen may relax 

and widen blood vessels, especially those around the heart. In animal studies, 

chemicals in danshen may also have protected the inner linings of arteries from damage. 

Some other research suggests it may increase the force of heartbeats and slow the heart rate 

slightly.In animal studies, Danshen has appeared to interfere with the development of liver fibrosis — 

the formation of scar-like fibers in the liver. Having chronic hepatitis and habitually drinking large amounts 

of alcoholic beverages are the major causes of liver fibrosis. Danshen may also increase 

blood flow into the liver, so the length of time that potentially damaging substances stay 

in the liver may be reduced. In addition Salvia miltiorrhiza inhibits a-glucosidase activity.[24] Salvia may stimulate dopamine release and has protective effects against free 

radical-induced cell toxicity.[27][28] S. miltiorrhiza stimulates increased osteogenesis in vivo (bone cell growth).[29] Danshen has been shown to potentiate the effects of the common anticoagulation drug warfarin, 

leading to gross anticoagulation and bleeding complications. 

Danshen should be avoided by those using warfarin.[31]

Evidence that ir can be effective in the treatment of eye disease:

Glaucoma is a disease of the retinal ganglion cells which make up the optic nerve. 

Over the years many different chemicals have been tested in laboratory animals to 

determine whether there is an effect on retinal cells. In one study of a rabbit model of glaucoma,intravenous 

Salvia miltiorrhiza was evaluated.  Notably, retinal ganglion cell damage in these rabbits 

was reduced by intravenous treatment with Salvia miltiorrhiza.[1]

Benefits seen in laboratory animals may be encouraging, but they don’t always 

translate to benefits in humans. The only study performed on humans using 

Salvia miltiorrhiza as a treatment of glaucoma used intramuscular injections of Salvia miltiorrhiza. 

In this study vision seemed to improve and visual fields appeared to stabilize.  

However, it is not known whether such an effect would be seen in those taking Salvia miltiorrhiza by mouth.[2

Product Name	Danshen Extract Powder	Specifcation	Appearance	Unit Price/kg
Botanical Source	Salvia miltiorrhiza Bge	10%	Brown yellow	$12.50
Active ingredient	Salvianolic Acid B	20%	Brown yellow	$42.70
Particle Size	98% Pass through 80 mesh	30%	Brown yellow	$61.10
Used Part	Red Sage Root	40%	Brown yellow	$135.00
CAS NO.	115939-25-8	50%	Light Brown	$168.30
Test Method	HPLC	60%	Light Brown	$205.50
Property	Solvable in water and ethanol
Packing	25kg Paper drum with double food grade bag inside
Function:	Antioxidant    anti-tumor    anti-aging     anticoagulation     protect myocardial   Prevent and teate Alzheimer's disease and cardiovascular disease
Application:	Widely used in health care products, foods, pharmaceuticals, cosmetics.

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